Lecturer in Biochemistry
Andy teaches on the Biology degree programme, helping to deliver the “Molecular Basis of Life”, “Cellular Basis of Life” and “Biomolecular Sciences” modules.
Andy has recently started at the University of Bolton (October 2013). He joined the University following 9 years as Post Doctoral Research Associate at the University of Manchester, where his primary research interest was the assembly and regulation of protein complexes in the extracellular matrix. Previously to this, he gained a PhD from the University of Nottingham in Pharmaceutical Sciences, with a project involving the biophysical characterisation of interactions between lipid and DNA in gene delivery systems.
Epithelial-mesenchymal status influences how cells deposit fibrillin microfibrils. Baldwin AK, Cain SA, Lennon R, Godwin A, Merry CLR, Kielty CM. In press, J. Cell Sci. 2013
Elastic fibres in health and disease. Baldwin AK, Simpson A, Steer R, Cain SA, Kielty CM. Expert Rev. Mol. Med. 2013 Aug Vol.15:e8 PMID - 23962539
Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions. Cain SA, McGovern A, Baldwin AK, Baldock C, Kielty CM. PLoS One. 2012;7(11):e48634. PMID - 23133647
Assembly of fibrillin microfibrils governs extracellular deposition of latent TGF beta. Massam-Wu T, Chiu M, Choudhury R, Chaudhry SS, Baldwin AK, McGovern A, Baldock C, Shuttleworth CA, Kielty CM. J. Cell Sci. 2010 Sep 1;123 (Pt 17):3006-18. PMID - 20699357
Differential regulation of elastic fiber formation by fibulin-4 and -5. Choudhury R, McGovern A, Ridley C, Cain SA, Baldwin A, Wang MC, Guo C, Mironov A Jr, Drymoussi Z, Trump D, Shuttleworth A, Baldock C, Kielty CM. J. Biol. Chem. 2009 Sep 4;284(36):24553-67. PMID - 19570982
Heparan sulfate regulates fibrillin-1 N- and C-terminal interactions. Baldwin AK, Cain SA, Mahalingam Y, Raynal B, Jowitt TA, Shuttleworth CA, Couchman JR, Kielty CM. J. Biol. Chem. 2008 Oct 3;283(40):27017-27. PMID - 18669635